UJI AKTIVITAS ANTIBAKTERI EKSTRAK BUAH TOMAT (Solanum lycopersicum L.) TERHADAP BAKTERI Propionibacterium acnes
DOI:
https://doi.org/10.61609/afamedis.v2i2.40Keywords:
Acne, Tomato (Solanum lycopersicum L.), Propionibacterium acnes, AntibacteriaAbstract
Acne is a skin infection disease, one of which is caused by bacteria. Treatment with antibiotics can cause resistance, so it is needed alternative treatment of natural ingredients and tomatoes (Solanum lycopersicum L.) is one of the natural ingredients that contain alkaloid compounds, flavonoids, saponins and tannins that are known to have an antibacterial effect. The purpose of this study was to find out the antibacterial activity of tomato extract against the growth of Propionibacterium acnes bacteria. Tomato fruit extract is divided into 3 concentration series (20%, 40% and 60%). Testing the taste of Propionibacterium acnes using diffusion method (Kirby and Bauer diffusion) by disc diffusion. Clindamycin is used as a positive control, and Aquadest as a negative control. The results of the study showed that the concentration of inhibition zone was 20% with an average of 1.08 mm, a concentration of 40% with an average of
3.74 mm, a concentration of 60% with an average of 5.14 mm, and clindamycin (positive control) with an averageof 9.15 mm and test data Kruskall-wallis obtained a value of 0.00 less than 0.05, it can be concluded that tomato fruit extract (Solanum lycopersicum L.) can inhibit the growth of Propionibacterium acnes bacteria with a significant difference andit is known that tomato fruit extract (Solanum lycopersicum L.) concentration of 60 % the most influential in inhibiting the growth of Propionibacterium acnes bacteria.
Keywords : Acne, Tomato (Solanum lycopersicum L.), Propionibacterium acnes, Antibacteria
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References
Alamsyah, Heru Kurniawan, Ita Widowati, and Agus Sabdono. 2014. “Agardh ) DARI PERAIRAN PULAU PANJANG JEPARA TERHADAP BAKTERI
Escherichia Coli DAN
Staphylococcus Epidermidis.” Journal Of Marine Research 3: 69–78.
Ardina, Y. 2007. “Pengembangan Formulasi Sediaan Gel Anti Jerawat Serta Penentuan Konsentrasi Hambat Minimum Ekstrak Daun Pepaya (Crica Papaya A Linn).” ITB Bandung. Betina. 1972. Analytical Microbiology. London: Academic Press.
Bonang G. 1992. Mikrobiologi Untuk Profesi Kesehatan. 16th ed. Jakarta: Buku Kedokteran EGC.
Dalimartha, and Setiawan. 2011. Khasiat Buah Dan Sayur. Jakarta: Penebar Swadaya.
Departemen Kesehatan RI. 1979. Farmakope Indonesia. Jakarta: Departemen Kesehatan RI.
Depkes RI. 2000. Parameter Standart Umum Ekstrak Tumbuhan Obat. Jakarta: Direktorat Jendral Pengawasan Obat dan Makanan.
Dewanjee. 2015. “Bioautography and Its Scope in the Field of Natural Product Chemistry.” Journal of Pharmaceutical Analysis.
Ditjen Pom Depkes RI. 2008. Cara Pembuatan Simplisia. Jakarta.
Djuanda, A, M Hamzah, and S Aisah. 1999. Ilmu Penyakit Kulit Dan Kelamin.
Jakarta: Balai Penerbit FKUI. Dwidjoseputro. 1985. Pengantar
Fisiologi Tumbuhan. Jakarta: PT. Gramedia Departemen Pertanian.
Eveline, Tagor marsilam Siregar, and Sanny. 2014. “Studi Aktivitas Antioksidan Pada Tomat ( Lycopersicon Esculentum ) Konvensional Dan Organik Selama Penyimpanan,” 22–28.
Gaspari, and Stephen. 2008. Clinical and Basic Immunodermatology. London: British Library Catakoguing.
Gaur. 2006. Process Optimization for The Production of Ethanol via Fermentation. Patiala: Thapar Institute of Engg and Technology.
Goeswin. 2007. Pengembangan Sediaan Farmasi. Bandung: IPB. Gunawan, D. 2010. Ilmu Obat Alam. Jakarta: Penebar Swadaya.
Hambali, Mudjalipah, Tambunan,
Pratiwi, and Hendroko. 2008. Teknologi Bioenergi. Jakarta: Agro Media.
Harahap, Mawali. 2009. Penyakit Kulit. Jakarta: Gramedia.
Harmita, and M Radji. 2008. Kepekaan Terhadap Antibiotik. 3rd ed. Jakarta: EGC.
Irianto Koes. 2006. Mikrobiologi : Menguak Dunia
Mikroorganisme. Bandung: CV. Yrama Widya.
Jawetz, Melnick, and Adelbergs. 2001. Mikrobiologi Kedokteran. Jakarta: Salemba Medika.
Maong, Reynal, Johnly Alfreds Rorong, and Feti Fatimah. 2015. “Aktivitas Ekstrak Buah Tomat (Lycopersicum Esculentum Mill) Sebagai Penstabil Oksigen Singlet Dalam Reaksi Fotooksidasi Asam Linoleat.” Jurnal MIPA 4 (2): 60.
https://doi.org/10.35799/jm.5.1. 2016.12288.
Muliyawan, and Suriana. 2013. Tentang Konsmetik. Jakarta: PT. Elex Media Komputindo.
Nugroho, R. 2013. “Terapi Topikal Clindamycin Dibandingkan Dengan Niacinamide + Zinc
Pada Acne Vulgaris.” Jurnal Kedokteran Diponegoro 2 (1):
108796.
Pelczar, Michael J, and E.C.S Chan. 1988. Dasar-Dasar Mikribiologi. Jakarta: UI Press.
Pratiwi, S.T. 2008. Mikrobiologi Farmasi. Jakarta: Erlangga.
Purba, Yosua Pandapot, M Ricky Ramadhian, Efrida Warganegara, and Sutyarso. 2018. “Pengaruh Pemberian Ekstrak Etanol Tomat (Solanum Lycopersicum) Terhadap
Pertumbuhan Salmonella Typhi.” Majority 7 (79): 80–85.
Riadi, Muchlisin. 2016.
“Pertumbuhan Bakteri.” 2016.
https://www.kajianpustaka.com/ 2016/04/pertumbuhan- bakteri.html.
Rowe, R. C., Sheskey. P.J., and Quinn. M.E. 2009. Handbook of Pharmaceutical Excipients 6th Edition. USA: Pharmaceutical Press and American Pharmaceutical Press.
Sembiring. 2007. Teknologi Penyiapan Simplisia Terstandar Tanaman Obat.
Bogor: balitro.
Soleha, Tri Umiana. 2015. “Uji Kepekaan Terhadap Antibiotik.” Juke Unila 5 (9): 120.
Syamsul, Eka, and Eka Purwanto. 2014. “UJI AKTIVITAS PERASAN BUAH MENTIMUN
(Cucumis Sativus L) SEBAGAI BIOLARVASIDA
TERHADAP LARVA NYAMUK
Aedes Aegypti L.” Jurnal Kimia Mulawarman 11 (2).
Titin Yuniarti. 2009. Ensiklopedia Tanaman Obat Traditional. Jakarta: Gadjah mada Press.
Tjay, T.H, and K Rahardja. 2007. Obat-Obat Penting, Khasiat, Penggunaan, Dan Efek-Efek Sampingnya. 5th ed. Jakarta: PT. Elex Media Komputindo.
Voigt. 1995. Buku Pelajaran Teknologi Farmasi. Edited by Soedani. Yogyakarta: UGM Press.
Waluyo. 2010. Teknik Dan Metode Dasar Dalam Mikrobiologi. Malang: UPT. Penerbitan Universitas Muhammadiyah Malang.
